Polyethylene Glycol 6000

Polyethylene Glycol 6000 – Premium Pharmaceutical Excipient from Avans NutriHealth

Avans NutriHealth Co., Ltd. provides high quality Polyethylene Glycol 6000 (Macrogol 6000, PEG 6000) with molecular weight of 5400–6600 g/mol and melting point of 55°C – 63°C. Our product is in compliance with CHP2020, USP40-NF35, EP9.0, ISO, HACCP, FSSC22000 and has pharmaceutical grade purity with lowest residual ethylene oxide and 1,4-dioxane. It's far white waxy stable flakes or granular powder with high-quality water solubility of more than 50% at 20°C. Our included manufacturing capability and rigorous great manage systems guarantee batch-to-batch consistency and whole technical help to satisfy your formula necessities.

What Is Polyethylene Glycol 6000?

This product is a high molecular weight non-ionic polyether molecule with the overall components H(OCH2CH2)nOH. It's miles a versatile pharmaceutical excipient used as a solubility enhancer and binder in solid dosage forms.

PEG 6000 is solid at normal temperature, unlike the lower molecular weight forms. This property makes it very suitable for solid dispersions, prolonged release tablets and precision formulation techniques. It is potential to inhibit crystallisation and maintain prescription drugs in an amorphous country improves the bioavailability of hydrophobic energetic pharmaceutical ingredients (APIs) on your formulations.

Its compatibility with most APIs and thermal stability during processing makes it a reliable option for pharmaceutical and nutraceutical applications.

Key Properties and Technical Specifications

Our product reveals distinct bodily and chemical traits that ensure consistent performance in disturbing programs.

The product is chemically inert and like minded with most lively elements. Its high thermal stability and non-toxicity profile align with international pharmacopeial requirements, making sure safety and reliability.

Core Applications in Pharmaceutical Manufacturing

The PEG 6000 powder can be used in several pharmaceutical and nutraceutical formulations:

Solid Dispersion Systems: It capabilities as a hydrophilic provider to improve the dissolution charge and bioavailability of poorly water soluble drugs. Prevents API crystallisation allowing for higher medicinal drug stability and quicker absorption.

Tablet Binder and Lubricant: Used in pill compression to increase flowability, lessen friability and guarantee uniform pill hardness. Manufacturing characteristics include anti-sticking and lubricity.

Sustained-Release Formulations: The release kinetics of the drug is managed through the polymer matrix which provides predictable therapeutic profiles for extended-launch dosage bureaucracy.

Suppository Base: Strong at ambient temperature however melts at low temperature. Perfect for rectal and vaginal suppositories. Provides high-quality administration and regulated drug launch.

Why Choose Avans NutriHealth for Your PEG 6000 Supply?

Integrated Manufacturing Excellence: As a group enterprise with dedicated manufacturing facilities we ensure production stability with reliable delivery schedules.

Full Technical Support: Our professional R&D and production teams can provide you with formulation assistance, compatibility studies and regulatory documentation support throughout your product development cycle.

Strict Quality Management: We guarantee a high level of quality control at each stage of manufacturing in order to meet international standards and ensure batch-to-batch consistency.

Flexible Supply Solutions: Whether you need bulk quantities or specialised packaging, our effective supply chain management matches your unique procurement needs.

Global Standards Compliance: We are committed to providing safe, natural and high quality raw materials. Our certifications (ISO, HACCP, FSSC22000) and pharmacopeial compliance are a testament to this.

Storage and Handling Recommendations

Proper storage ensures the functioning qualities of Polyethylene Glycol 6000 powder:

Hold in sealed, airtight containers in a chilly, dry place underneath 30 °C. Hygroscopicity may set off caking. Defend from moisture exposure. Shop in the sunshine and high stress.

For accelerated dissolution during formulation, increase water temperature to 60–70°C and employ high-shear stirring. This process cuts the dissolving time very dramatically in comparison to ambient settings.

Hold coping with equipment smooth and dry to avoid contamination. The product is strong under normal occasions of garage and has a recommended shelf existence of 24 months when saved properly.

Quality Control and Compliance Assurance

Avans NutriHealth implements stringent quality control protocols throughout production. Our testing procedures include:

· Molecular Weight Distribution Analysis (GPC): Ensures viscosity control and batch consistency.

· Hydroxyl Value Verification: Confirms chemical reactivity profile for formulation accuracy.

· Moisture Content Testing (Karl Fischer): Prevents caking and degradation during storage.

· Trace Impurity Analysis: Headspace GC testing for ethylene oxide and 1,4-dioxane ensures safety compliance.

· pH Testing of 5% Aqueous Solution: Verifies compatibility with acid-sensitive APIs.

Our product is compliant with International Pharmacopoeia (USP-NF, EP, BP, CP) and offers high purity and low polydispersity index for precise formulations. To help with your regulatory submissions and quality assurance process, we provide detailed Certificates of Analysis (CoA) for each batch.

FAQ

Q: Why does the powder occasionally cake up in storage?

A: Usually due to moisture absorption or storage at high pressure. Always store in sealed containers in a cool, dry place below 30°C.

Q: How can PEG 6000 help to increase the bioavailability of drugs?

A: It forms a hydrophilic matrix, preventing API crystallisation and keeping medicines in the amorphous state for quicker breakdown and absorption.

Q: Is this product edible?

A: Yeah. Our product complies with pharmaceutical excipient safety regulations and is Generally Recognised as Safe (GRAS) for food and pharmaceutical uses.

Q: Is it possible to replace PEG 4000 with PEG 6000 in formulations?

A: PEG 6000 is of comparable chemical composition but has a greater melting point and viscosity. Performance equivalence may require a change in formulation ratios.

Q: What accelerates dissolving in the formulation?

A: Raising the temperature of water up to 60–70°C and using high shear agitation greatly shortens the time required for dissolution in comparison with processing at room temperature.

Contact Us for Premium Polyethylene Glycol 6000

Ready to enhance your pharmaceutical formulations with Polyethylene Glycol 6000? Email us at Lillian@avansnutri.com to discuss your specific requirements.