Guanosine 5'-Monophosphate Disodium Salt Powder
Appearance: White powder
Origin: China
Stocks: in stock
Certificate: HALAL,ISO,USDA, HACCP, FSSC22000,etc.
CAS no: 5550 -12 -9
Application: Food additives
- Product Description
Guanosine 5'-Monophosphate Disodium Salt Powder
Avans NutriHealth Co., Ltd. delivers industrial-grade Guanosine 5'-Monophosphate Disodium Salt Powder manufactured through advanced enzymatic hydrolysis and bacterial fermentation technology. Our product meets FCC V, USP, and EP pharmacopoeial standards with assay purity ranging from 98.0% to 102.0%. This white crystalline powder demonstrates exceptional thermal stability during high-temperature processing and offers synergistic flavor amplification that increases umami intensity by 10 to 100 times when combined with MSG or IMP.
With certifications including HALAL, ISO, USDA, HACCP, and FSSC22000, our manufacturing entity ensures consistent quality and reliable supply. The product maintains a pH balance between 7.0 and 8.5, making it compatible with diverse food matrices.

What Is Guanosine 5'-Monophosphate Disodium Salt Powder?
This high quality nucleotide salt is a very effective flavour potentiator. It is called E627 in the food additive nomenclature. It works directly on glutamate receptors on the tongue to improve umami flavour characteristics.
The substance tackles key formulation difficulties in modern food processing. It enables salt reduction with no impact on taste perception. It reduces flat taste profiles in retorted foods and lowers metallic or bitter off-notes in processed products”.
This ingredient uniquely boosts umami, adding depth and complexity to your creations. The synergistic effect provides a “umami explosion,” as industry pros term it, when paired correctly with complementing flavour enhancers.

Technical Specifications
Parameter | Specification |
CAS Number | 5550-12-9 |
Molecular Formula | C10H12N5Na2O8P |
Molecular Weight | 407.19 g/mol (anhydrous) |
Appearance | White crystalline powder |
Assay (HPLC) | 98.0% - 102.0% |
Solubility in Water | >20g/100ml at 20°C |
pH (5% solution) | 7.0 - 8.5 |
Loss on Drying | <25.0% (heptahydrate form) |
Transmittance | >95% at 430nm |
Lead Content | <1ppm |
Arsenic Content | <2ppm |
Microbial Limits | Salmonella/E. Coli negative |
Key Properties and Advantages
Guanosine 5'-Monophosphate Disodium Salt Powder exhibits superior physical and chemical characteristics for industrial applications. The colorless crystals or white powder form shows hygroscopicity only under high relative humidity conditions.
It is very soluble in water (>20g/100ml at 20°C) and can easily be incorporated into liquid systems. Low solubility in ethanol. This allows some freedom in formulation for some applications.
Compared to other flavour agents, thermal stability is a major benefit. HTST and retorting technologies are available for your processing activities without structural damages. That stability is important for consistent flavour delivery in shelf-stable products.
It is stable over the pH range from neutral to slightly acidic. This adaptability increases the range of applications to different food matrices and processing conditions.

Industrial Applications
Savoury Food Processing & Sauces
You'll find this ingredient in lots of fast noodle flavouring sachets, soy sauces and dried soup bases. It completes the flavour profiles and increases the mouthfeel experience called kokumi.
Its compensating effects are especially useful in low-sodium formulations. Your products satisfy taste and meet the needs of health-conscious consumers for lower salt content.
Infant Nutrition and Supplements
It is an exogenous source of nucleotides that mimics the nucleotide profile of human breast milk in newborn formulae. It is involved in the development of the immune system in neonates.
It supports the formation of good gut flora and aids in lipid metabolism. These are the physiological benefits of why it is valuable in paediatric nutrition applications where you need to support healthy newborn development.
Pharmaceutical Synthesis
The high purity powder is an important intermediate for the manufacture of anti-virus drugs. Compounds such as Acyclovir and Ribavirin require a certain arrangement of phosphate groups which this substance may deliver.
Achieve consistent quality meeting demanding purity standards for your pharmaceutical manufacturing of active medicinal ingredients.

Storage and Handling Recommendations
Store in a cool, dry place out of direct sunlight. Sealed containers keep the powder flowing, and prevent moisture uptake. Temperature management (15-25°C) optimises shelf life.
Your facility should operate a first in, first out inventory rotation protocol. Proper handling methods help to limit the risks of cross-contamination and maintain product quality throughout the supply chain.
Wear suitable protection equipment when handling. The substance has a low toxicity, but typical food-grade handling methods are employed to assure workplace safety and product integrity.

Quality Control Standards
Procurement must have a strict inspection process to assure product integrity. Assay verification: HPLC proves that content surpasses 98.0% ensuring dosage efficiency for your formulations.
The transmittance of 5% solutions is normally greater than 95% at 430 nm. Clarity means no insoluble contaminants or carbon residues that could spoil the appearance of clear liquids or broths.
Loss on drying controls ensure precise dosing by weight and prevent caking. Lead and arsenic heavy metal testing complies with JECFA and Codex regulations, preserving your brand reputation and customer safety.
Microbial testing ensures pathogen free material. And every batch is fully tested before it’s released to ensure it meets worldwide food safety standards.

FAQ
Q: What makes this ingredient different from standard MSG?
A: It provides synergistic amplification when combined with glutamate-based enhancers, creating exponentially stronger umami effects than MSG alone. The nucleotide structure interacts with specific taste receptors for unique flavor enhancement.
Q: Can it withstand high-temperature processing?
A: Yes, thermal stability allows use in HTST and retort processing without degradation. Your heat-treated products maintain consistent flavor profiles throughout manufacturing.
Q: Is it suitable for clean-label formulations?
A: The ingredient qualifies as a naturally-derived nucleotide when produced through fermentation. It supports label claims for natural flavor enhancement in appropriate regulatory contexts.
Q: What is the typical usage rate?
A: Application rates range from 0.01% to 0.05% depending on the food matrix. Your formulation team can optimize dosing based on desired intensity and synergistic combinations with other enhancers.
Q: Does it contain allergens?
A: When produced through bacterial fermentation of corn or tapioca, the purified product contains no major allergens. You should verify allergen status with specific batch documentation.
Partner With Avans NutriHealth Today
Ready to enhance your formulations with premium Guanosine 5'-Monophosphate Disodium Salt Powder? Contact us at Lillian@avansnutri.com for technical specifications, samples, or pricing information.












