Luteolin Powder

High-Purity Luteolin Powder: Premium Flavonoid Extract for Advanced Formulations

Avans NutriHealth Co., Ltd. delivers pharmaceutical-grade Luteolin Powder with standardized purity levels ranging from 90% to 98%, verified by HPLC analysis. This yellow crystalline powder is produced by our fully integrated manufacturing company, Avans (Qingdao) NutriHealth Technology Co., Ltd., and is derived from optimised botanical sources such as Sophora japonica buds. Our production procedure minimises solvent residue and prevents allergic protein carryover.

We have ISO, HACCP, FSSC22000, HALAL and USDA certifications and we control the quality during the extraction and purification process. Each production batch is tested for assay content, heavy metals, microbiological limits and residual solvents according to ICH Q3C requirements. With our own plant, we can assure a steady supply with stock on hand and a shelf life of 24-36 months under proper storage.

Superior Bioactive Properties

Our product performs outstandingly in a wide range of application scenarios. The compound has a very high free radical scavenging capacity because of the hydroxyl groups at C3' and C4'. This molecular structure provides more stability to similar flavonoids under physiological conditions.

The lipophilic nature (LogP ~2.53) allows for efficient blood-brain barrier permeability. This property is advantageous especially in neuroprotective formulations to regulate glial cells. Compared to many flavonoids, the aglycone form has better absorption rates and higher efficacy per gram.

The powder is a strong PDE4 inhibitor, which targets key anti-inflammatory pathways. Its enhanced cell membrane penetration properties enable targeted results in mast cell stabilisation applications. These functional benefits address formulation issues and allow therapeutic efficiency at reduced dose requirements.

Technical Specifications

Diverse Application Solutions

Pharmaceutical Development 

Our high purity powder is an active medicinal ingredient in anti-inflammatory and neuroprotective pharmaceuticals. Consistent quality meets the precise formulation requirements for clinical applications.

Nutraceutical Formulations

Our product is used by dietary supplement manufacturers for cardiovascular health, brain function support and inflammation management products. The micronised grade is formulated for optimum dispersion in capsule and tablet forms.

Functional Food Integration 

Food technologists are adding this flavonoid to health-oriented goods as a means to reduce oxidative stress. Its stability profile preserves bioactivity throughout product shelf life.

Cosmetic Applications

Skincare formulators use its antioxidant and anti-inflammatory properties in anti-aging serums and soothing treatments. Small particle size makes them easy to disperse in emulsion systems.

Formulation Enhancement Solutions

Avans NutriHealth solves the inherent poor water solubility problem with the help of advanced processing techniques. Our micronised powder (D90 < 10μm) shows a remarkable improvement in dispersion properties in aqueous media. Co-formulation with phospholipid complexes or cyclodextrins is recommended for better bioavailability.

Nano-emulsification technology or lipid carrier systems are beneficial for the applications of liquid formulation. Luteolin Powder with sunflower lecithin or olive oil mix for activated lymphatic transport routes for increased absorption. Our technical support team provides guidance on the best formulation approach.

The powder is chemically stable under a wide variety of pH and temperature settings. Light resistant packaging maintains the flavonoid structure throughout storage and transportation. QA protocols ensure each batch is consistent to ensure reliable manufacturing processes.

Quality Assurance & Compliance

Our group enterprise organization integrates R&D, production and quality control under unified management systems. Multi-stage testing is conducted by experienced technical teams during the production cycles. For each batch, a COA is provided which outlines the purity, identity and safety parameters.

We do heavy metals monitoring, pesticide residues monitoring and microbiological contamination in a very strict way. Residual solvent analysis guarantees that the drug product meets international pharmaceutical standards. Our manufacturing plant is subject to periodic audit by other parties to verify the validity of the certification.

The quality management system emphasises traceability from the procurement of raw materials to the delivery of the completed product. Advanced analytical instrumentation including HPLC, GC-MS and ICP-MS support precision testing techniques. This holistic approach offers natural, safe products that meet global regulatory standards.

FAQ

Q: What botanical sources do you use for extraction?

A: We primarily extract from Sophora japonica buds and Arachis hypogaea shells, optimized for maximum yield and minimal residue. Sophora-derived material is preferred for EU/US markets to avoid allergen declaration requirements.

Q: How do you address water solubility challenges?

A: We offer micronized grades with D90 < 10μm particle size. Formulating with phospholipid complexes, cyclodextrins, or lipid carriers significantly enhances dispersion and absorption in aqueous systems.

Q: Does the powder penetrate the blood-brain barrier?

A: Yes, the product exhibits high BBB permeability, making it ideal for neuroprotective applications targeting neuroinflammation and cognitive support formulations.

Q: What distinguishes your powder from luteolin-7-glucoside?

A: Our aglycone form provides faster absorption and higher potency compared to glycoside variants. This allows lower dosage requirements while maintaining therapeutic effectiveness.

Q: How should the powder be stored for optimal stability?

A: Store in airtight, light-resistant containers at controlled room temperature. Avoid prolonged UV exposure and moisture contact to maintain assay content throughout the 24-36 month shelf life.

Partner with Avans NutriHealth

Ready to enhance your formulations with premium-quality Luteolin Powder? Contact us today at Lillian@avansnutri.com to discuss your specific requirements and request product samples.